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About this book introduction not everyone is a friend of the manifold abbreviations that have by now become a part of the scientific language of medicine. dictionary of abbreviations in medical sciences

Neuroblastoma tumorigenesis is characterized by ectopic histone deacetylase HDAC expression, decreased expression of MAP2 and of the autophagy protein markers Beclin1 and LC3 inducing neurite retraction.

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Then we used inducible cell models to analyze the impact of CHL1 on neuroblastoma growth. Here we present that genetic or pharmacologic inhibition with novel inhibitors of histone demethylases is able to inhibit proliferation of neuroblastoma.

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